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May 18,  · Balanced translocation, or reciprocal translocation, is a type of chromosomal abnormality that can cause recurrent miscarriages in some couples. couple conceives via in-vitro fertilization along with gene testing of the embryos to be sure that they do not have an unbalanced translocation. Shaffer LG. Chromosome Abnormalities and Genetic.

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Jan 11,  · Unbalanced Robertsonian translocations are a significant cause of mental retardation and fetal wastage. The majority of homologous rearrangements of chromosome 21 in Down syndrome have been shown to be isochromosomes. Aside from chromosome 21, very little is known about other acrocentric homologous rearrangements. Some cases of Down syndrome arise in the children of parents who carry a Robertsonian translocation that involves chromosome Down syndrome can also be caused by having . Congenital anterior polar cataracts can be associated with chromosomal abnormalities. We treated two sisters with this condition who had the same unbalanced translocation between the long arm of chromosome 3 and the short arm of chromosome Their mother had a balanced translocation between those chromosomes but had no cataract.

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Jan 27,  · Chromosome analysis or karyotyping is a test that evaluates the number and structure of a person’s chromosomes in order to detect abnormalities. If it is not, then it is called an unbalanced translocation. Genetic Rearrangement: With this, genetic material is present on a chromosome but not in its usual location. A person could have both.